Density Regulated Protein antibody

Catalog No. ABIN4908699

Product Details anti-Density Regulated Protein Antibody

Target: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Density Regulated Protein antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: This DENR antibody is generated from a mouse immunized with a recombinant protein of human DENR.

Clone: 2C9

Isotype: IgG2b

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for Density Regulated Protein

Target: Density Regulated Protein (DENR) (Density-Regulated Protein (DENR))

Alternative Name: DENR (DENR Products)

Synonyms: DRP antibody, DRP1 antibody, SMAP-3 antibody, DENR antibody, 1500003K04Rik antibody, drp antibody, drp1 antibody, smap-3 antibody, MGC79758 antibody, MGC107862 antibody, im:6891640 antibody, zgc:113309 antibody, zgc:92629 antibody, denr antibody, Denr antibody, DDBDRAFT_0205981 antibody, DDBDRAFT_0266779 antibody, DDB_0205981 antibody, DDB_0266779 antibody, density regulated re-initiation and release factor antibody, density-regulated protein L homeolog antibody, density-regulated protein antibody, Density-regulated protein antibody, density regulated reinitiation and release factor antibody, DENR antibody, denr.L antibody, Denr antibody, denr antibody, EHI_065830 antibody, CpipJ_CPIJ009942 antibody, MCYG_07531 antibody, Tsp_00169 antibody

Background:

Synonyms: DRP, DRP1, SMAP-3, Density-regulated protein, Protein DRP1, Smooth muscle cell-associated protein 3, DENR, H14

Background: May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation, promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

Gene ID: 8562

UniProt: O43583