CREB3L4 antibody

Catalog No. ABIN4908306

Product Details anti-CREB3L4 Antibody

Target: CREB3L4 (cAMP Responsive Element Binding Protein 3-Like 4 (CREB3L4))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CREB3L4 antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Rat

Purification: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This CREB3L4 antibody is generated from mice immunized with a recombinant between 1-300 amino acids from the region of human CREB3L4.

Clone: 5C1

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CREB3L4

Target: CREB3L4 (cAMP Responsive Element Binding Protein 3-Like 4 (CREB3L4))

Alternative Name: CREB3L4 (CREB3L4 Products)

Background:

Synonyms: JAL, hJAL, ATCE1, CREB3, CREB4, AIBZIP, Cyclic AMP-responsive element-binding protein 3-like protein 4, cAMP-responsive element-binding protein 3-like protein 4, Androgen-induced basic leucine zipper protein, Attaching to CRE-like 1, Cyclic AMP-responsive element-binding protein 4, CREB-4, cAMP-responsive element-binding protein 4, Transcript induced in spermiogenesis protein 40, Tisp40, CREB3L4

Background: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity).

Gene ID: 148327

UniProt: Q8TEY5

Pathways: Thyroid Hormone Synthesis