CBY1/PGEA1 antibody (AA 51-126)

Catalog No. ABIN4907492

Product Details anti-CBY1/PGEA1 Antibody

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Binding Specificity: AA 51-126

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBY1/PGEA1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CBY1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CBY1/PGEA1

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Alternative Name: CBY1 (CBY1 Products)

Synonyms: chibby antibody, cby antibody, arb1 antibody, pgea1 antibody, pigea14 antibody, pigea-14 antibody, hs508i15a antibody, C22orf2 antibody, CBY antibody, HS508I15A antibody, PGEA1 antibody, PIGEA-14 antibody, PIGEA14 antibody, 1110014P06Rik antibody, PGEA14 antibody, Pgea1 antibody, chibby homolog 1 S homeolog antibody, chibby homolog 1 antibody, chibby family member 1, beta catenin antagonist antibody, cby1.S antibody, cby1 antibody, CBY1 antibody, Cby1 antibody

Background:

Synonyms: CBY, arb1, PGEA1, C22orf2, PIGEA14, PIGEA-14, HS508I15A, Protein chibby homolog 1, ARPP-binding protein, Cytosolic leucine-rich protein, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, CBY1, HRIHFB2025

Background: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

Gene ID: 25776

UniProt: Q9Y3M2