COQ8A antibody

Catalog No. ABIN4907317

Product Details anti-COQ8A Antibody

Target: COQ8A (Coenzyme Q8A (COQ8A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This COQ8A antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CABC1 monoclonal antibody is generated from mouse immunized with CABC1 recombinant protein.

Clone: 6C1

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for COQ8A

Target: COQ8A (Coenzyme Q8A (COQ8A))

Alternative Name: CABC1 (COQ8A Products)

Background:

Synonyms: COQ8, ADCK3, ARCA2, CABC1, SCAR9, COQ10D4, Atypical kinase ADCK3, mitochondrial, Chaperone activity of bc1 complex-like, Chaperone-ABC1-like, aarF domain-containing protein kinase 3, PP265

Background: Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:25498144). Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway (PubMed:25498144). Shows an unusual selectivity for binding ADP over ATP (PubMed:25498144).

Gene ID: 56997

UniProt: Q8NI60