BANP antibody

Catalog No. ABIN4906466

Product Details anti-BANP Antibody

Target: BANP (Protein BANP (BANP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BANP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP.

Clone: 4C2

Isotype: IgG1

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BANP

Target: BANP (Protein BANP (BANP))

Alternative Name: BANP (BANP Products)

Synonyms: smar1 antibody, smarbp1 antibody, MGC76079 antibody, MGC89601 antibody, BEND1 antibody, SMAR1 antibody, SMARBP1 antibody, AA408158 antibody, zgc:111954 antibody, BTG3 associated nuclear protein antibody, Btg3 associated nuclear protein antibody, BTG3 associated nuclear protein L homeolog antibody, banp antibody, BANP antibody, Banp antibody, banp.L antibody

Background:

Synonyms: BEND1, SMAR1, SMARBP1, Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BANP

Background: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity).

Gene ID: 54971

UniProt: Q8N9N5