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Angiotensin II antibody (AbBy Fluor® 594)

Ang II Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal AbBy Fluor® 594
Catalog No. ABIN2809731
  • Target See all Angiotensin II (Ang II) Antibodies
    Angiotensin II (Ang II)
    Reactivity
    Human, Mouse, Rat
    Host
    • 27
    • 3
    Rabbit
    Clonality
    • 25
    • 4
    • 1
    Polyclonal
    Conjugate
    • 12
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Angiotensin II antibody is conjugated to AbBy Fluor® 594
    Application
    • 12
    • 10
    • 10
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Specificity
    The immunogen used generate this antibody is DRVYIHPF, corresponding to amino acids 34-41 of human Angiotensinogen.
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    MAP conjugated synthetic peptide derived from human Angiotensin II
    Isotype
    IgG
    Top Product
    Discover our top product Ang II Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Angiotensin II (Ang II)
    Alternative Name
    Angiotensin II (Ang II Products)
    Synonyms
    ANHU antibody, SERPINA8 antibody, ANRT antibody, Ang antibody, AngII antibody, PAT antibody, AI265500 antibody, AngI antibody, Aogen antibody, Serpina8 antibody, angiotensinogen antibody, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody, AGT antibody, Agt antibody
    Background

    Synonyms: Alpha 1 antiproteinase, antitrypsin, Ang II, ANG III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, Angiotensinogen serpin peptidase inhibitor, clade A member 8, ANHU, Pre angiotensinogen, Serine or cysteine proteinase inhibitor, Serpin A8, SERPINA8, AT-2, AT-II, ANGT_HUMAN.

    Background: Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. Angiotensin-2: acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone. Angiotensin-3: stimulates aldosterone release. Angiotensin 1-7: is a ligand for the G-protein coupled receptor MAS1. Has vasodilator and antidiuretic effects. Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.

    Gene ID
    183
    Pathways
    JAK-STAT Signaling, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity
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