SQLE antibody
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- Target See all SQLE Antibodies
- SQLE (Squalene Epoxidase (SQLE))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SQLE antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd.
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human SQLE.
- Isotype
- IgG
- Top Product
- Discover our top product SQLE Primary Antibody
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- Application Notes
- WB 1:500-1:2000 , IHC 1:20-1:50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C.
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- Target
- SQLE (Squalene Epoxidase (SQLE))
- Alternative Name
- SQLE (SQLE Products)
- Synonyms
- An03g03770 antibody, AO090701000685 antibody, AI323792 antibody, squalene epoxidase antibody, SQLE antibody, ANI_1_450034 antibody, AOR_1_1218114 antibody, CC1G_03987 antibody, BDBG_08449 antibody, MCYG_02365 antibody, TERG_05717 antibody, Sqle antibody
- Gene ID
- 6713
- UniProt
- Q14534
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