RHOH antibody (C-Term)
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- Target See all RHOH Antibodies
- RHOH (Ras Homolog Family Member H (RHOH))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RHOH antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Specificity
- Reacts with human RhoH protein
- Purification
- Purified (protein A)
- Immunogen
- Synthetic peptide derived from C terminal domain of human RhoH
- Top Product
- Discover our top product RHOH Primary Antibody
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- Application Notes
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- IHC : 1/200 to 1/2 000 - WB : 1/500 to 1/5 000 - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- Storage
- 4 °C/-20 °C
- Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 24 months
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- Target
- RHOH (Ras Homolog Family Member H (RHOH))
- Alternative Name
- rho-Related GTP-Binding Protein RhoH (RHOH Products)
- Synonyms
- ARHH antibody, TTF antibody, 5830400A04Rik antibody, AU019774 antibody, Arhh antibody, ras homolog family member H antibody, RHOH antibody, Rhoh antibody
- Background
- Negative regulator of hematopoietic progenitor cell proliferation, survival and migration. Critical regulator of thymocyte development and T-cell antigen receptor (TCR) signaling by mediating recruitment and activation of ZAP70. Required for phosphorylation of CD3Z, membrane translocation of ZAP70 and subsequent activation of the ZAP70-mediated pathways. Essential for efficient beta-selection and positive selection by promoting the ZAP70-dependent phosphorylation of the LAT signalosome during pre-TCR and TCR signaling. Crucial for thymocyte maturation during DN3 to DN4 transition and during positive selection.
- UniProt
- Q15669
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