WWP1 antibody (Internal Region)
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- Target See all WWP1 Antibodies
- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This WWP1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- Reacts with human WWP1 protein
- Purification
- Purified (protein A)
- Immunogen
- Synthetic peptide derived from internal part of human WWP1 protein
- Top Product
- Discover our top product WWP1 Primary Antibody
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- Application Notes
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only :
WB(1:200 - 1:2000) - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Concentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- Storage
- 4 °C/-20 °C
- Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 24 months
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- Target
- WWP1 (WW Domain Containing E3 Ubiquitin Protein Ligase 1 (WWP1))
- Alternative Name
- NEDD4-Like E3 Ubiquitin-Protein Ligase WWP1 (WWP1 Products)
- Synonyms
- AIP5 antibody, Tiul1 antibody, hSDRP1 antibody, 8030445B08Rik antibody, SDRP1 antibody, WWP1 antibody, aip5 antibody, tiul1 antibody, hsdrp1 antibody, WW domain containing E3 ubiquitin protein ligase 1 antibody, WWP1 antibody, Wwp1 antibody, wwp1 antibody
- Background
- E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1, the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF
- UniProt
- Q9H0M0
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