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CD81 antibody

CD81 Reactivity: Human, Rabbit, Cat FACS, WB, IP, Func, IHC (p), ICC Host: Mouse Monoclonal M38 unconjugated
Catalog No. ABIN4888503
  • Target See all CD81 Antibodies
    CD81
    Reactivity
    • 124
    • 98
    • 35
    • 16
    • 16
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rabbit, Cat
    Host
    • 68
    • 61
    • 29
    • 12
    • 3
    • 1
    Mouse
    Clonality
    • 121
    • 47
    • 3
    Monoclonal
    Conjugate
    • 72
    • 21
    • 17
    • 15
    • 7
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD81 antibody is un-conjugated
    Application
    • 123
    • 78
    • 44
    • 37
    • 29
    • 28
    • 27
    • 27
    • 15
    • 13
    • 13
    • 13
    • 5
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    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Specificity
    The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
    Cross-Reactivity (Details)
    Human, Feline (Cat), Rabbit
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Endotoxin Level
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    Immunogen
    MOLT-4 (human T-ALL cell line)
    Clone
    M38
    Isotype
    IgG1
    Top Product
    Discover our top product CD81 Primary Antibody
  • Application Notes
    Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
    Flow cytometry: recommended dilution: 1 μg/mL.
    Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Preservative
    Azide free
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    CD81
    Alternative Name
    CD81 (CD81 Products)
    Synonyms
    Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody
    Background
    CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28
    Gene ID
    975
    UniProt
    P60033
    Pathways
    Inositol Metabolic Process, Hepatitis C
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