8-OHDG antibody

Catalog No. ABIN488679

Product Details anti-8-OHDG Antibody

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Reactivity: Please inquire

Host: Mouse

Clonality: Monoclonal

Conjugate: This 8-OHDG antibody is un-conjugated

Application: ELISA, Affinity Purification (AP), Immunostaining (ISt)

Specificity: Recognizes markers of oxidative damage to DNA (8-hydroxy-2?-deoxyguanosine,8-hydroxyguanine and 8-hydroxyguanosine).

Purification: affinity purified

Immunogen: 8-hydroxy-guanosine-BSA and - casein conjugates

Clone: 15A3

Isotype: IgG2a

Application Details

Application Notes: Recommended Dilution needs to be determined for each application.

Comment:

protocol for immunostaining using this antibody can be found here

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: protein G purified IgG2B in PBS, pH 7.4 with 0.09 % sodium azide and 50 %glycerol at concentration 0.65 mg/mL

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.
Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes.

Storage: -20 °C

References for anti-8-OHDG antibody (ABIN488679)

Haigh, Drew: "Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation?" in: Biochemical and biophysical research communications, Vol. 461, Issue 3, pp. 494-500, (2015) (PubMed).

Bobal, Otevrel, Poborilova, Vaverkova, Csollei, Babula: "Application of BY-2 cell model in evaluating an effect of newly prepared potential calcium channel blockers." in: Pakistan journal of pharmaceutical sciences, Vol. 28, Issue 4, pp. 1281-93, (2015) (PubMed).

Pilger, Rüdiger: "8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures." in: International archives of occupational and environmental health, Vol. 80, Issue 1, pp. 1-15, (2006) (PubMed).

Target Details for 8-OHDG

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Alternative Name: 8-Hydroxyguanosine (8-OHDG Products)

Target Type: Chemical

Background: Oxidative derivate of guanosine is called 8-Hydroxyguanosine (8OHdG) and is used as a popular biomarker of oxidative stress.