Vip antibody (Middle Region)

Catalog No. ABIN4886760

Product Details anti-Vip Antibody

Target: Vip (Vasoactive Intestinal Peptide (Vip))

Binding Specificity: AA 81-107, Middle Region

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vip antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for VIP peptides(VIP) detection. Tested with IHC-P in Human,Mouse,Rat.

Sequence: HADGVFTSDF SKLLGQLSAK KYLESLM

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for VIP peptides(VIP) detection. Tested with IHC-P in Human,Mouse,Rat.
Gene Name: vasoactive intestinal peptide
Protein Name: VIP peptides

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human VIP (81-107aa HADGVFTSDFSKLLGQLSAKKYLESLM), different from the related mouse and rat sequences by four amino acids.

Isotype: IgG

Application Details

Application Notes: IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Vip antibody (ABIN4886760)

Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Target Details for Vip

Target: Vip (Vasoactive Intestinal Peptide (Vip))

Alternative Name: VIP (Vip Products)

Synonyms: PHM27 antibody, vip1 antibody, zgc:171463 antibody, VIP antibody, vip-A antibody, PHI antibody, vasoactive intestinal peptide antibody, vasoactive intestinal peptide L homeolog antibody, vasoactive intestinal polypeptide antibody, VIP antibody, Vip antibody, vip antibody, vip.L antibody

Background: Vasoactive intestinal peptide, also known as PHM27 or VIP, is a peptide hormone containing 28 amino acid residues. This gene is mapped to 6q25. The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Synonyms: PHM27 | PHM-27 | PHM 27 | PHV42 | VIP | VIP peptides | P01282

Gene ID: 7432

UniProt: P01282

Pathways: Hormone Activity, cAMP Metabolic Process