HLA-DPB1 antibody (AA 30-258)
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- Target See all HLA-DPB1 Antibodies
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
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Binding Specificity
- AA 30-258
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HLA-DPB1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1) detection. Tested with WB in Human,Mouse,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: major histocompatibility complex, class II, DP beta 1
Protein Name: HLA class II histocompatibility antigen, DP beta 1 chain - Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human HLA-DPB1 recombinant protein (Position: R30-A258).
- Isotype
- IgG
- Top Product
- Discover our top product HLA-DPB1 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).
: "
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S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).
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- Target
- HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1 (HLA-DPB1))
- Alternative Name
- HLA-DPB1 (HLA-DPB1 Products)
- Synonyms
- PATR-DPB1 antibody, B-LB antibody, B-LB2 antibody, B-LB21 antibody, BLB1 antibody, GSP-BLB1 antibody, DPB1 antibody, HLA-DP antibody, HLA-DP1B antibody, HLA-DPB antibody, major histocompatibility complex, class II, DP beta 1 antibody, Major histocompatibility complex class II beta chain BLB1 antibody, PATR-DPB1 antibody, BLB1 antibody, HLA-DPB1 antibody
- Background
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HLA class II histocompatibility antigen, DP(W2) beta chain is a protein that in humans is encoded by the HLA-DPB1 gene. HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Synonyms: DPB1 | HLA-DP | HLA-DP1B | HLA-DPB | P04440 - Gene ID
- 3115
- UniProt
- P04440
- Pathways
- TCR Signaling, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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