CCT2 antibody (AA 414-535)

Catalog No. ABIN4886512

Product Details anti-CCT2 Antibody

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Binding Specificity: AA 414-535

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for T-complex protein 1 subunit beta(CCT2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for T-complex protein 1 subunit beta(CCT2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: chaperonin containing TCP1 subunit 2
Protein Name: T-complex protein 1 subunit beta

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TCP1 beta recombinant protein (Position: E414-C535). Human TCP1 beta shares 95.9% and 93.4% amino acid (aa) sequence identity with mouse and rat TCP1 beta, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CCT2

Target: CCT2 (Chaperonin Containing TCP1, Subunit 2 (Beta) (CCT2))

Alternative Name: CCT2 (CCT2 Products)

Synonyms: fa26a01 antibody, fc58a11 antibody, CHUNP6883 antibody, wu:fa26a01 antibody, wu:fc58a11 antibody, cct2 antibody, MGC89448 antibody, CCT2 antibody, 99D8.1 antibody, CCT-beta antibody, CCTB antibody, PRO1633 antibody, TCP-1-beta antibody, Cctb antibody, chaperonin containing TCP1 subunit 2 antibody, chaperonin containing TCP1, subunit 2 (beta) antibody, chaperonin containing Tcp1, subunit 2 (beta) antibody, T-complex protein 1 subunit beta antibody, CCT2 antibody, cct2 antibody, Cct2 antibody, cct-2 antibody

Background: T-complex protein 1 subunit beta (TCP1 beta) is a protein that in humans is encoded by the CCT2 gene. The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: 99D8.1 | CCT 2 | CCT2 | CCT beta | CCT-beta | CCTB | HEL S 100n | PRO1633 | TCP 1 beta | TCP-1-beta | P78371

Gene ID: 10576

UniProt: P78371