C1QBP antibody (AA 190-282)

Catalog No. ABIN4886491

Product Details anti-C1QBP Antibody

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Binding Specificity: AA 190-282

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Complement component 1 Q subcomponent-binding protein, mitochondrial(C1QBP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Complement component 1 Q subcomponent-binding protein, mitochondrial(C1QBP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: complement component 1, q subcomponent binding protein
Protein Name: Complement component 1 Q subcomponent-binding protein, mitochondrial

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human GC1q R recombinant protein (Position: E190-Q282). Human GC1q R shares 92.5% and 93.5% amino acid (aa) sequence identity with mouse and rat GC1q R, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for C1QBP

Target: C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

Alternative Name: C1QBP (C1QBP Products)

Synonyms: SF2 antibody, X38k antibody, gC1qR antibody, C1QBP antibody, GC1QBP antibody, HABP1 antibody, SF2p32 antibody, gC1Q-R antibody, p32 antibody, AA407365 antibody, AA986492 antibody, D11Wsu182e antibody, P32 antibody, gC1qBP antibody, Habp1 antibody, complement C1q binding protein antibody, complement component 1, q subcomponent binding protein S homeolog antibody, complement component 1, q subcomponent binding protein antibody, C1QBP antibody, c1qbp.S antibody, LOC100227158 antibody, C1qbp antibody

Background: Complement component 1 Q subcomponent-binding protein, mitochondrial is a protein that in humans is encoded by the C1QBP gene. This gene is mapped to 17p13.3 in a region conserved with mouse chromosome 11. The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.

Synonyms: C1qBP | GC1Q R | GC1QR | GC1QBP | GC1q R protein | GC1q-R protein | HABP 1 | HABP1 | p32 | p33 | SF2p32 | Q07021

Gene ID: 708

UniProt: Q07021

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly