APOA1 antibody (AA 25-267)
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- Target See all APOA1 Antibodies
- APOA1 (Apolipoprotein A-I (APOA1))
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Binding Specificity
- AA 25-267
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This APOA1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P, ELISA in Human.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Apolipoprotein A-I(APOA1) detection. Tested with WB, IHC-P, ELISA in Human.
Gene Name: apolipoprotein A-I
Protein Name: Apolipoprotein A-I - Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human APOA1 recombinant protein (Position: D25-Q267). Human APOA1 shares 64% and 61.7% amino acid (aa) sequence identity with mouse and rat APOA1, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product APOA1 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- APOA1 (Apolipoprotein A-I (APOA1))
- Alternative Name
- APOA1 (APOA1 Products)
- Synonyms
- Alp-1 antibody, Apoa-1 antibody, Brp-14 antibody, Ltw-1 antibody, Lvtw-1 antibody, Sep-1 antibody, Sep-2 antibody, Sep2 antibody, apoA-I antibody, apoa antibody, apoa1 antibody, cb49 antibody, wu:fb33f01 antibody, zgc:103718 antibody, MGC64335 antibody, MGC89745 antibody, Apo-AI antibody, ApoA-I antibody, APOA1 antibody, LOC100136573 antibody, apoa-i antibody, ApoAI antibody, apolipoprotein A1 antibody, apolipoprotein A-I antibody, apolipoprotein A-Ia antibody, apolipoprotein A-I S homeolog antibody, apolipoprotein A4 antibody, APOA1 antibody, Apoa1 antibody, apoa1a antibody, apoa1.S antibody, apoa1 antibody, LOC100136573 antibody, apoa-i antibody, apoa4 antibody
- Background
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Apolipoprotein A-1, also known as APOA1, is a human protein with a specific role in lipid metabolism. It binds to lipopolysaccharide or endotoxin, and has a major role in the anti-endotoxin function of HDL. The gene is mapped to 11q23. And it is a single polypeptide chain with 243 amino acid residues of known primary amino acid sequence. The ApoA-I protein promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. ApoA-I is also isolated as a prostacyclin (PGI2) stabilizing factor, and thus may have an anticlotting effect. Defects in the gene encoding it are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Additionally, ApoA-I overexpression promotes macrophage-specific reverse cholesterol transport.
Synonyms: Apo AI | APOA 1 | ApoA I | APOA1 | ApoA-I | Apo-AI | Apolipoprotein A I | Apolipoprotein A1 | Apolipoprotein AI | Apolipoprotein A-I | Apolipoprotein A-I(1-242) | ProapoA-I | Proapolipoprotein A-I | Truncated apolipoprotein A-I | P02647 - Gene ID
- 335
- UniProt
- P02647
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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