ADH1A antibody (AA 213-375)

Catalog No. ABIN4886427

Product Details anti-ADH1A Antibody

Target: ADH1A (Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A))

Binding Specificity: AA 213-375

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADH1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Alcohol dehydrogenase 1A(ADH1A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Alcohol dehydrogenase 1A(ADH1A) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: alcohol dehydrogenase 1A (class I), alpha polypeptide
Protein Name: Alcohol dehydrogenase 1A

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ADH1A recombinant protein (Position: K213-F375). Human ADH1A shares 87.1% and 82.8% amino acid (aa) sequence identity with mouse and rat ADH1A, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ADH1A

Target: ADH1A (Alcohol Dehydrogenase 1A (Class I), alpha Polypeptide (ADH1A))

Alternative Name: ADH1A (ADH1A Products)

Synonyms: ADC1 antibody, ADH1 antibody, ADH antibody, ARVP antibody, AVP-NPII antibody, AVRP antibody, VP antibody, adh-1 antibody, ADH-AA antibody, AI194826 antibody, Adh-1 antibody, Adh-1-t antibody, Adh-1e antibody, Adh-1t antibody, Adh-3e antibody, Adh1-e antibody, Adh1-t antibody, Adh1tl antibody, Adh3-e antibody, Adh antibody, Adh1a antibody, Adh1c antibody, Adh1 antibody, Dvir\\Adh antibody, Dvir\\GJ18208 antibody, GJ18208 antibody, dvir_GLEANR_2771 antibody, ADH-1 antibody, ADH1B antibody, alcohol dehydrogenase ADH1 antibody, alcohol dehydrogenase 1A (class I), alpha polypeptide antibody, arginine vasopressin antibody, alcohol dehydrogenase 1 antibody, alcohol dehydrogenase 1A antibody, alcohol dehydrogenase 1 (class I) antibody, Alcohol dehydrogenase 1 antibody, alcohol dehydrogenase 1C (class I), gamma polypeptide antibody, ADH1 antibody, ADH1A antibody, AVP antibody, adh1 antibody, LOC744064 antibody, Adh1 antibody, Dvir\Adh1 antibody, ADH1C antibody

Background: Alcohol dehydrogenase 1A is an enzyme that in humans is encoded by the ADH1A gene. This gene encodes a member of the alcohol dehydrogenase family. The encoded protein is the alpha subunit of class I alcohol dehydrogenase, which consists of several homo- and heterodimers of alpha, beta and gamma subunits. Alcohol dehydrogenases catalyze the oxidation of alcohols to aldehydes. This gene is active in the liver in early fetal life but only weakly active in adult liver. And this gene is found in a cluster with six additional alcohol dehydrogenase genes, including those encoding the beta and gamma subunits, on the long arm of chromosome 4. Mutations in this gene may contribute to variation in certain personality traits and substance dependence.

Synonyms: ADH | ADH1 | ADH1A | Alcohol dehydrogenase 1 | Alcohol dehydrogenase 1A | Aldehyde reductase | P07327

Gene ID: 124

UniProt: P07327