Species reactivity (expected):Mouse, Canine, Bovine. Species reactivity (tested):Human.
Purification
Affinity chromatography
Immunogen
Peptide with sequence C-EPLLKRLGAAKH, from the C Terminus of the protein sequence according to NP_078862.2, NP_683702.1, NP_683703.1, NP_683704.1, NP_683705.1, NP_683706.1, NP_683707.1.
OSBPL9
Reactivity: Human
IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 350
Application Notes
Peptide ELISA: 1/32000. Immunohistochemistry on paraffin sections: Human Lung shows staining of alveolarmacrophages. Recommended concentration: 2 - 4 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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Background
The OSBPL9 gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. OSBPL9 appears to be in a distinct OSBP subfamily and shares relatively little homology in the sterol-binding domain with other OSBPs. Multiple transcript variants have been identified, most of which encode distinct isoforms. This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Multiple transcript variants, most of which encode distinct isoforms, have been identified.Synonyms: ORP-9, ORP9, OSBP-related protein 9, OSBP4, Oxysterol-binding protein-related protein 9