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PRDM1 antibody (C-Term)
PRDM1
Reactivity: Human, Mouse, Rat, Dog, Pig, Cow
WB, EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-PRDM1 Antibody
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Target
See all PRDM1 Antibodies
PRDM1
(PR Domain Containing 1, with ZNF Domain (PRDM1))
Binding Specificity
All epitopes for PRDM1 antibodies
C-Term
Reactivity
All reactivities for PRDM1 antibodies
Human, Mouse, Rat, Dog, Pig, Cow
Host
All hosts for PRDM1 antibodies
Goat
Clonality
All clonalities for PRDM1 antibodies
Polyclonal
Conjugate
All conjugates for PRDM1 antibodies
This PRDM1 antibody is un-conjugated
Application
All applications for PRDM1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody is expected to recognize both reported isoforms (NP_001189.2 and NP_878911.1).
Cross-Reactivity (Details)
Species reactivity (expected):Mouse, Rat, Canine, Porcine, Bovine. Species reactivity (tested):Human.
Purification
Affinity chromatography
Immunogen
Peptide with sequence C-KVKQETVEPMDP, from the C Terminus of the protein sequence according to NP_001189.2, NP_878911.1.
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Alternatives
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anti-PR Domain Containing 1, with ZNF Domain (PRDM1) (Middle Region) antibody
PRDM1
Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Horse, Guinea Pig
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Peptide ELISA: 1/2000. Western blot: Approx 100 kDa band observed in Human Brain (cerebellum) lysates(calculated MW of 91.0 kDa according to NP_001189.2 and of 76.8 according toNP_878911.1). Recommended concentration: 1 - 3 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target Details for PRDM1
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Target
PRDM1
(PR Domain Containing 1, with ZNF Domain (PRDM1))
Alternative Name
PRDM1 / BLIMP1 (PRDM1 Products )
Synonyms
GB11750 antibody, CG5249 antibody, Dmel\\CG5249 antibody, blimp-1 antibody, dBlimp-1 antibody, dBlimp1 antibody, Blimp-1 antibody, Blimp1 antibody, nrd antibody, prdm1 antibody, ubo antibody, wu:fb99c12 antibody, zgc:91885 antibody, MGC52536 antibody, PRDM1 antibody, blimp1 antibody, xblimp1 antibody, prdi-bf1 antibody, BLIMP1 antibody, PRDI-BF1 antibody, ZNFPR1A1 antibody, PR/SET domain 1 antibody, probable serine/threonine-protein kinase DDB_G0282963 antibody, CG5249 gene product from transcript CG5249-RF antibody, blimp-1 antibody, PR domain containing 1a, with ZNF domain antibody, PR domain 1 S homeolog antibody, B lymphocyte induced maturation protein 1 antibody, PR domain 1 antibody, PR domain containing 1, with ZNF domain antibody, PRDM1 antibody, LOC408295 antibody, Blimp-1 antibody, CpipJ_CPIJ007425 antibody, prdm1a antibody, prdm1.S antibody, prdm1 antibody, Prdm1 antibody
Background
PRDM1/Blimp1 is a repressor of beta-interferon gene expression. This action is exerted by binding to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. The transcription of this gene is increased upon virus induction.Synonyms: BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain zinc finger protein 1, PR domain-containing protein 1, PRDI-BF1, PRDI-binding factor 1, Positive regulatory domain I-binding factor 1
Gene ID
639
NCBI Accession
NP_001189
UniProt
O75626
Pathways
Regulation of Muscle Cell Differentiation
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