LPP antibody (Internal Region)

Catalog No. ABIN487982

Product Details anti-LPP Antibody

Target: LPP (Lipoma-preferred partner (LPP))

Binding Specificity: Internal Region

Reactivity: Human, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This LPP antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to LPP.

Cross-Reactivity (Details): Species reactivity (expected):Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-RNDSDPTYGQQGHP, from the internal region of the protein sequence according to NP_005569.1.

Application Details

Application Notes: Peptide ELISA: 1/16000. Western blot: Approx 85 kDa band observed in Human Placenta lysates and in lysates ofcell line HepG2 (calculated MW of 65.5 kDa according to NP_005569.1). The observedmolecular weight corresponds to earlier findings with different antibodies from othercommercial sources. Recommended concentration: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for LPP

Target: LPP (Lipoma-preferred partner (LPP))

Alternative Name: LPP (LPP Products)

Synonyms: 9430020K16Rik antibody, AA959454 antibody, AU024130 antibody, B130055L10Rik antibody, C79715 antibody, D630048H16 antibody, LIM domain containing preferred translocation partner in lipoma antibody, LPP antibody, Lpp antibody

Background: LPP (LIM containing lipoma preferred partner), is a scaffolding protein which contains three LIM domains at its carboxy terminus, preceded by a proline rich pre LIM region containing a number of protein interaction domains. LPP localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity. The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.Synonyms: LIM domain-containing preferred translocation partner in lipoma, LPP, Lipoma-preferred partner

Gene ID: 4026

NCBI Accession: NP_005569

UniProt: Q93052