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Insulin C-Peptide antibody

Reactivity: Mouse, Rat ELISA Host: Mouse Monoclonal CC34 unconjugated
Catalog No. ABIN472131
  • Target See all Insulin C-Peptide products
    Insulin C-Peptide
    Reactivity
    Mouse, Rat
    Host
    • 11
    • 4
    • 1
    Mouse
    Clonality
    • 12
    • 4
    Monoclonal
    Conjugate
    • 9
    • 6
    • 1
    This Insulin C-Peptide antibody is un-conjugated
    Application
    • 9
    • 8
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    ELISA
    Specificity
    Recognizes rat C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Recognizes rat and mouse C-peptide I and rat C-peptide II with equal affinity. Reacts weakly with mouse C-peptide II. It does not recognize rat proinsulin. May be used as a capture antibody in ELISA assays for rat or mouse C-peptides I or II.
    Purification
    Affinity purified
    Immunogen
    Fragments of rat C-peptide conjugated to a carrier protein.
    Clone
    CC34
    Isotype
    IgG1
  • Application Notes
    Approved: ELISA, SwELISA

    Usage: ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA ?to detect rat C-peptide I together with LS-C58408 as a detection reagent. These sandwich ELISA combinations are not suitable for the detection of mouse C-peptide I or II.
    Comment

    Target Species of Antibody: Rat

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Short term: -20°C
    Long term: -20°C.
  • Target
    Insulin C-Peptide
    Abstract
    Insulin C-Peptide Products
    Synonyms
    IDDM2 antibody, ILPR antibody, IRDN antibody, MODY10 antibody, insulin antibody, INS antibody
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