CD66acd antibody
CEACAM1/3/6
Reactivity: Human, Rhesus Monkey
FACS, IHC (fro), IHC
Host: Rat
Monoclonal
YTH71-3
unconjugated
1 image
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- Target See all CD66acd (CEACAM1/3/6) Antibodies
- CD66acd (CEACAM1/3/6) (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/3/6 (CEACAM1/3/6))
- Reactivity
- Human, Rhesus Monkey
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD66acd antibody is un-conjugated
- Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)
- Specificity
- Recognizes 3 members of the human CD66 family, namely CD66a, also known as Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1 or CEACAM1. Clone YTH71.3 also recognizes CD66c, known as Carcinoembryonic antigen-related cell adhesion molecule 6 or Non-specific cross-reacting antigen. In addition the clone also recognizes CD66d which in turn is also known as Carcinoembryonic antigen-related cell adhesion molecule 3 or CGM1. CD66 family members are single pass, type 1 membrane glycoproteins bearing a single domain and a varying number of domains. Clone YTH71.3 recognizes epitopes in the of these CD66 family members. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma. CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithelial cells in diseases including COPD and emphysema.
- Purification
- Affinity purified
- Immunogen
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Human lymphocytes.
Type of Immunogen: Cells - Clone
- YTH71-3
- Isotype
- IgG2a
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anti-Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/3/6 (CEACAM1/3/6) antibody
CEACAM1/3/6 Reactivity: Human, Monkey FACS, IHC (fro), IHC (p) Host: Rat Monoclonal unconjugated
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- Application Notes
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Approved: Flo, IHC, IHC-Fr
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL. Method sheets are available on request. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- CD66acd (CEACAM1/3/6) (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/3/6 (CEACAM1/3/6))
- Alternative Name
- CD66acd (CEACAM1/3/6 Products)
- Synonyms
- CD66c antibody, CEAL antibody, NCA antibody, carcinoembryonic antigen related cell adhesion molecule 6 antibody, carcinoembryonic antigen-related cell adhesion molecule 6 antibody, CEACAM6 antibody, Ceacam6 antibody
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