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CD66acd antibody

CEACAM1/3/6 Reactivity: Human, Rhesus Monkey FACS, IHC (fro), IHC Host: Rat Monoclonal YTH71-3 unconjugated
Catalog No. ABIN472061
  • Target See all CD66acd (CEACAM1/3/6) Antibodies
    CD66acd (CEACAM1/3/6) (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/3/6 (CEACAM1/3/6))
    Reactivity
    Human, Rhesus Monkey
    Host
    • 2
    Rat
    Clonality
    • 1
    Monoclonal
    Conjugate
    • 2
    This CD66acd antibody is un-conjugated
    Application
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (IHC)
    Specificity
    Recognizes 3 members of the human CD66 family, namely CD66a, also known as Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1 or CEACAM1. Clone YTH71.3 also recognizes CD66c, known as Carcinoembryonic antigen-related cell adhesion molecule 6 or Non-specific cross-reacting antigen. In addition the clone also recognizes CD66d which in turn is also known as Carcinoembryonic antigen-related cell adhesion molecule 3 or CGM1. CD66 family members are single pass, type 1 membrane glycoproteins bearing a single domain and a varying number of domains. Clone YTH71.3 recognizes epitopes in the of these CD66 family members. CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma. CD66a is also expressed in the human alveolar adenocarcinoma cell line A549 and may play a role in Moraxella catarrhalis induced apoptosis of pulmonary epithelial cells in diseases including COPD and emphysema.
    Purification
    Affinity purified
    Immunogen
    Human lymphocytes.

    Type of Immunogen: Cells
    Clone
    YTH71-3
    Isotype
    IgG2a
  • Application Notes
    Approved: Flo, IHC, IHC-Fr

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1 x 10^6 cells in 100 μL. Method sheets are available on request.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • Target
    CD66acd (CEACAM1/3/6) (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/3/6 (CEACAM1/3/6))
    Alternative Name
    CD66acd (CEACAM1/3/6 Products)
    Synonyms
    CD66c antibody, CEAL antibody, NCA antibody, carcinoembryonic antigen related cell adhesion molecule 6 antibody, carcinoembryonic antigen-related cell adhesion molecule 6 antibody, CEACAM6 antibody, Ceacam6 antibody
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