Chromosome 10 Open Reading Frame 116 (C10orf116) (C-Term) antibody

Catalog No. ABIN4620378

Product Details

Target: Chromosome 10 Open Reading Frame 116 (C10orf116)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects APM2 (C-term).

Purification: Affinity chromatography

Immunogen: Synthetic peptide derived from human APM2 protein

Isotype: IgG

Application Details

Application Notes: Western blot (1: 400 starting dilution). Positive control: Adipose tissue, cornea and liver.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Target Details

Target: Chromosome 10 Open Reading Frame 116 (C10orf116)

Alternative Name: APM2 (C10orf116 Products)

Synonyms: AFRO antibody, APM2 antibody, C10orf116 antibody, apM-2 antibody, adipogenesis regulatory factor antibody, ADIRF antibody

Background: APM2 is an ~8 kDa protein which until recently was found only in the EST data base but never as an expressed protein. APM2 has since been shown to be associated with cisplatin resistance in cell lines. APM2 is not found in cisplatin sensitive cell lines. These data implicate APM2 in the development of cisplatin resistance in tumor cells.Synonyms: Adipose most abundant gene transcript 2 protein, C10orf116

Gene ID: 10974

NCBI Accession: NP_006820

UniProt: Q15847

Pathways: Positive Regulation of fat Cell Differentiation