GLI1 antibody
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- Target See all GLI1 Antibodies
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLI1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects Zinc Finger Protein GLI1, found in testis, myometrium and fallopian tube.
- Purification
- Affinity chromatography
- Immunogen
- Synthetic peptide derived from human zinc finger protein GLI1
- Top Product
- Discover our top product GLI1 Primary Antibody
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- Application Notes
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Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline with 0.08 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
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- Target
- GLI1 (Zinc Finger Protein GLI1 (GLI1))
- Alternative Name
- GLI1 (GLI1 Products)
- Synonyms
- GLI antibody, Gli antibody, Gli-1 antibody, gli1.1 antibody, AV235269 antibody, Zfp-5 antibody, Zfp5 antibody, GLI family zinc finger 1 antibody, GLI family zinc finger 1 S homeolog antibody, GLI-Kruppel family member GLI1 antibody, GLI1 antibody, Gli1 antibody, gli1.S antibody, gli1 antibody
- Background
- Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes during normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.Synonyms: GLI, GLI-1, Glioma-associated oncogene, Oncogene GLI, Zinc finger protein GLI1
- Gene ID
- 2735
- NCBI Accession
- NP_001153517
- UniProt
- P08151
- Pathways
- Hedgehog Signaling, Dopaminergic Neurogenesis
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