SGPP1 antibody
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- Target See all SGPP1 Antibodies
- SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SGPP1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody reacts to Sphingosine 1-Phosphate Phosphatase 1.
- Purification
- Affinity Purified
- Immunogen
- Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 1 protein.
- Isotype
- IgG
- Top Product
- Discover our top product SGPP1 Primary Antibody
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- Application Notes
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Western Blot: 1: 200, Tissue lysate should be used at 10-50 g/lane. Positive Control: Human brain lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- Phosphate buffered saline with 0.08 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- The antibody can be shipped on dry ice. Store (in aliquots) at -20 °C only.
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- Target
- SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))
- Alternative Name
- SGPP1 (SGPP1 Products)
- Synonyms
- SGPP1 antibody, MGC142448 antibody, sgpp1 antibody, SPPase1 antibody, AI463453 antibody, SPP antibody, SPP1 antibody, Spph1 antibody, Spp1 antibody, sphingosine-1-phosphate phosphatase 1 antibody, SGPP1 antibody, sgpp1 antibody, Sgpp1 antibody
- Background
- Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.Synonyms: SPPase1, Sphingosine-1-phosphatase 1, Sphingosine-1-phosphate phosphatase 1
- Gene ID
- 81537
- NCBI Accession
- NP_110418
- UniProt
- Q9BX95
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