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CXCR4 antibody (AA 14-40)

CXCR4 Reactivity: Human, Mouse WB, ELISA, IHC, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN461996
  • Target See all CXCR4 Antibodies
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Binding Specificity
    • 18
    • 15
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 14-40
    Reactivity
    • 131
    • 83
    • 66
    • 21
    • 11
    • 11
    • 10
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 113
    • 22
    • 9
    • 5
    • 1
    Goat
    Clonality
    • 120
    • 30
    Polyclonal
    Conjugate
    • 96
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CXCR4 antibody is un-conjugated
    Application
    • 110
    • 50
    • 46
    • 35
    • 27
    • 26
    • 25
    • 25
    • 18
    • 11
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Brand
    IHC-plus™
    Specificity
    This antibody binds to CXCR4 receptor on mouse spleen leukocytes as determined by immunocytochemistry.
    Predicted Reactivity
    Percent identity by BLAST analysis: Mouse (100%) Rat (93%) Baboon, Monkey, Marmoset, Elephant, Rabbit (81%).
    Purification
    Immunoaffinity purified
    Immunogen
    YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to the N-terminal extracellular domain of mouse CXCR4 receptor. Percent identity by BLAST analysis: Mouse (100%), Rat (93%), Baboon, Monkey, Marmoset, Elephant, Rabbit (81%).
    Top Product
    Discover our top product CXCR4 Primary Antibody
  • Application Notes
    Approved: ELISA (1:25000), IHC, IHC-P (5 μg/mL), WB (1:500)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.
    Comment

    Target Species of Antibody: Mouse

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Phosphate buffered saline, 1 mg/mL BSA, 0.1 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Alternative Name
    CXCR4 (CXCR4 Products)
    Background
    Name/Gene ID: CXCR4
    Subfamily: Chemokine
    Family: GPCR

    Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR
    Gene ID
    7852
    UniProt
    P61073
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
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