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TYR antibody (C-Term)

Name: TYR antibody (C-Term)
SKU: ABIN453446
Price: 768 USD
Availability: InStock

TYR Reactivity: Human WB, IF, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated

Western blot analysis of Tyrosinase Antibody (C-term) Cat. (TYR antibody (C-Term))

Fow Cytometric analysis of A375 cells using Tyrosinase Antibody (C-term) Cat. (TYR antibody (C-Term))

FACS

Confocal immunofluorescent analysis of Tyrosinase Antibody (C-term) Cat. (TYR antibody (C-Term))

Immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue using Tyrosinase Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. (TYR antibody (C-Term))

IHC (p)

4 images

Catalog No. ABIN453446

Datasheet as PDF

Target See all TYR Antibodies

TYR (Tyrosinase (TYR))
Binding Specificity
15

6

5

5

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reactivity
95

22

20

6

3

3

2

2

2

2

2

2

1

1

1
Human
Host
60

36
Rabbit
Compatible Secondaries
Clonality
51

46
Polyclonal
Conjugate
52

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This TYR antibody is un-conjugated
Application
47

37

27

27

22

20

17

13

13

9

7

4

4

3

1

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity

This antibody recognizes Human Tyrosinase (TYR). Other species not tested.

Purification

Saturated Ammonium Sulfate (SAS) precipitation

Immunogen

KLH conjugated synthetic peptide selected from the C-terminal region of human TYR

Isotype

Ig Fraction

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TYR Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB19155 unconjugated

anti-Tyrosinase (TYR) (AA 1-377) antibody
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anti-Tyrosinase (TYR) (C-Term) antibody
TYR Reactivity: Human, Mouse, Rat WB, IF, IHC, ELISA, ICC Host: Rabbit Polyclonal unconjugated

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TYR Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB19154 unconjugated

anti-Tyrosinase (TYR) antibody
TYR Reactivity: Human IF, IHC, FACS, StM Host: Mouse Monoclonal T311 unconjugated

anti-Tyrosinase (TYR) antibody
TYR Reactivity: Human WB, IF, FACS, IHC (p) Host: Mouse Monoclonal T311 unconjugated

Application Notes

ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.25 mg/mL

Buffer

PBS, 0.09 % (W/V) Sodium Azide

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

TYR (Tyrosinase (TYR))

Abstract

TYR Products

Synonyms

sandy antibody, zgc:109705 antibody, TYR antibody, TYRO antibody, tyr antibody, LOC100136546 antibody, CMM8 antibody, OCA1A antibody, OCAIA antibody, SHEP3 antibody, albino antibody, c antibody, skc35 antibody, C antibody, tyrosinase antibody, TYRosinase antibody, tyrosinase S homeolog antibody, tyr antibody, tyr-5 antibody, tyr.S antibody, TYR antibody, Celal_3121 antibody, Halhy_4121 antibody, Mesop_2736 antibody, LOC100136546 antibody, Tyr antibody

Background

TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation.Synonyms: LB24-AB, Monophenol monooxygenase, SK29-AB, Tumor rejection antigen AB

Molecular Weight

60393 Da

Gene ID

7299

NCBI Accession

NP_000363

UniProt

P14679