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CD130/gp130 antibody (pTyr905)
IL6ST
Reactivity: Human
EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CD130/gp130 Antibody
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Target
See all CD130/gp130 (IL6ST) Antibodies
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Binding Specificity
All epitopes for CD130/gp130 antibodies
pTyr905
Reactivity
All reactivities for CD130/gp130 antibodies
Human
Host
All hosts for CD130/gp130 antibodies
Rabbit
Clonality
All clonalities for CD130/gp130 antibodies
Polyclonal
Conjugate
All conjugates for CD130/gp130 antibodies
This CD130/gp130 antibody is un-conjugated
Application
All applications for CD130/gp130 antibodies
Enzyme Immunoassay (EIA)
Specificity
This antiobdy reacts to Tyr905 phosphorylated CD130 / IL6ST.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y905 of human IL6ST
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Alternatives
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Application Details
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Application Notes
ELISA: 1/1,000. Dot blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CD130/gp130
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Target
CD130/gp130 (IL6ST)
(Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST))
Alternative Name
CD130 / IL6ST (IL6ST Products )
Synonyms
CD130 antibody, CDW130 antibody, GP130 antibody, IL-6RB antibody, 5133400A03Rik antibody, AA389424 antibody, BB405851 antibody, D13Ertd699e antibody, gp130 antibody, Ac1055 antibody, Gp130 antibody, Il-6rb antibody, IL-6 antibody, interleukin 6 signal transducer antibody, IL6ST antibody, Il6st antibody, il6st antibody
Background
IL6ST is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein.Synonyms: IL-6R-beta, IL6 receptor beta, Interleukin-6 receptor subunit beta
Gene ID
3572
NCBI Accession
NP_002175
UniProt
P40189
Pathways
JAK-STAT Signaling , Cellular Glucan Metabolic Process , Autophagy , Smooth Muscle Cell Migration , Cancer Immune Checkpoints
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