LRRC32 antibody (AA 240-269)

Catalog No. ABIN453046

Product Details anti-LRRC32 Antibody

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Binding Specificity: AA 240-269

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC32 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects GARP at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 240~269 amino acids from the Center region of Human GARP Genename: LRRC32

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on paraffin sections: 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for LRRC32

Target: LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))

Alternative Name: LRRC32 / GARP (LRRC32 Products)

Synonyms: D11S833E antibody, GARP antibody, AI426318 antibody, D11S833Eh antibody, D7H11S833E antibody, EG434215 antibody, Garp antibody, leucine rich repeat containing 32 antibody, LRRC32 antibody, Lrrc32 antibody

Background: GARP, also known as leucine rich repeat containing 32, is a type I membrane protein with twenty-two leucine-rich repeats and a short intracytoplasmic region. GARP was identified based on the analysis of gene expression profiling of Treg and Th cells following TCR stimulation. Since GARP is expressed in CD4+, CD25+, FoxP3+ cells (Tregs), it may be a candidate for cell surface marker for Treg cells.Synonyms: D11S833E, Garpin, Glycoprotein A repetitions predominant, Leucine-rich repeat-containing protein 32

Molecular Weight: 71979 Da

Gene ID: 2615

NCBI Accession: NP_001122394

UniProt: Q14392

Pathways: Activated T Cell Proliferation