FKBP1B antibody (N-Term)

Catalog No. ABIN453013

Product Details anti-FKBP1B Antibody

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP1B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects FKBP1B at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human FKBP1B

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for FKBP1B

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Alternative Name: FKBP1B / FKBP9 (FKBP1B Products)

Background: FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.Synonyms: FK506-binding protein 1B, FKBP12.6, FKBP1L, Immunophilin FKBP12.6, OTK4, PPIase FKBP1B, Peptidyl-prolyl cis-trans isomerase FKBP1B, Rotamase, h-FKBP-12

Molecular Weight: 11783 Da

Gene ID: 2281

NCBI Accession: NP_004107

UniProt: P68106

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity