Cathepsin H antibody (N-Term)

Catalog No. ABIN452890

Product Details anti-Cathepsin H Antibody

Target: Cathepsin H (CTSH)

Binding Specificity: AA 32-62, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin H antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Human Cathepsin H at N-term.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 32~62 amino acids from the N-terminal region of human CTSH

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Cathepsin H

Target: Cathepsin H (CTSH)

Alternative Name: Cathepsin H (CTSH Products)

Background: The protein is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of its gene has been correlated with malignant progression of prostate tumors.Synonyms: CPSB, CTSH, Cathepsin B3

Molecular Weight: 37378 Da

Gene ID: 1512

NCBI Accession: NP_004381

UniProt: P09668

Pathways: Positive Regulation of Endopeptidase Activity