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CD41, CD61 antibody

Reactivity: Human EIA, WB Host: Mouse Monoclonal 291 unconjugated
Catalog No. ABIN452604
  • Target See all CD41, CD61 Antibodies
    CD41, CD61 (CD41,CD61)
    Reactivity
    • 11
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 19
    Mouse
    Clonality
    • 19
    Monoclonal
    Conjugate
    • 9
    • 4
    • 4
    • 1
    • 1
    This CD41, CD61 antibody is un-conjugated
    Application
    • 16
    • 8
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    Enzyme Immunoassay (EIA), Western Blotting (WB)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Characteristics
    Synonyms: Platelet Membrane GPIIb-IIIa Complex, CD41b, CD61, GP3A, GPIIIa, GPIIIb, GTA, HPA3,Integrin alpha 2b, Integrin beta 3
    Purification
    Affinity Chromatography on Protein G.
    Immunogen
    10e9 Human platelets suspension. The supernatant fluid from positive clones was screened by ELISA coated with washedplatelets.
    Clone
    291
    Isotype
    IgG2b
    Top Product
    Discover our top product CD41, CD61 Primary Antibody
  • Application Notes
    This GPIIb/IIIa antibody is Suitable for use in ELISA and Western Blot. Use of this Monoclonal antibody at a concentration of 10-20 μg/mL (culture supernatants)will allow visualization of NP 40 solubilized human normal platelets. The titer of purified ascites was determined by ELISA coated with 100 μL of 1x10e8 washedplatelets.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
    Buffer
    0.01 M PBS, pH 7.2 without preservatives.
    Preservative
    Without preservative
    Storage
    -20 °C
    Storage Comment
    Store the antibody at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    CD41, CD61 (CD41,CD61)
    Abstract
    CD41, CD61 Products
    Background
    The integrins are a family of more than 23 heterodimeric transmembrane proteins that mediate cell-cell adhesions as well as cell-substratum adhesions and signal transduction processes. Integrins are heterodimers consisting of noncovalently associated alpha and beta subunits. CD61 non-covalently associates with CD41 (alpha Ilb integrin) and is expressed by megakaryocytes and platelets. The CD61/CD41 complex acts as a receptor for such adhesive ligands as fibronectin, fibrinogen and von Willebrand factor during platelet stimulation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
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