CD1d1 antibody

Catalog No. ABIN4369392

Product Details anti-CD1d1 Antibody

Target: CD1d1 (CD1D1)

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD1d1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Chicken CD1.1

Characteristics: Mouse Anti-Chicken CD1.1-UNLB

Purification: Purified

Immunogen: Lymphocytes from the bursa of Fabricius of outbred chickens

Clone: CB3

Isotype: IgG1

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD1d1

Target: CD1d1 (CD1D1)

Alternative Name: CD1.1 (CD1D1 Products)

Synonyms: Cd1 antibody, Cd1d antibody, AI747460 antibody, CD1.1 antibody, Cd1a antibody, Ly-38 antibody, CD1d1 molecule antibody, CD1d1 antigen antibody, Cd1d1 antibody

Background: CD1 molecules, like MHC I and II, play an equally important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells 1. Chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution 2. Two proteins have been identified: CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells (B cells and some macrophages) and CD8a+ cells (some T and NK cells). CD1.2 is expressed in TCR1 + cells (γ δ cells) but is nearly undetectable in TCR2+ and TCR3+ cells (α and β T cells) 1.