Glutamate Receptor 1 antibody (Ser863)

Catalog No. ABIN401628

Product Details anti-Glutamate Receptor 1 Antibody

Target: Glutamate Receptor 1 (GLUR1)

Binding Specificity: Ser863

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Immunofluorescence (IF)

Specificity: GluR1 Antibody detects endogenous levels of total GluR1 protein.

Purification: Affinity chromatography

Immunogen: Synthesized non-phosphopeptide derived from human GluR1 around the phosphorylation site of serine 863 (R-N-SP-G-A)

Application Details

Application Notes: Immunofluorescence: 1/100 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: Glutamate Receptor 1 / GLUR1 (GLUR1 Products)

Background: Glutamate receptor 1 (AMPA) belongs to the glutamate-gated ion channel and binds AMPA, glutamate and kainate. L-Glutamate is the major excitatory neurotransmitter in the mammalian CNS, acting through both ligand gated ion channels (ionotropic receptors, composed of subunits GluR1-4) and G-protein coupled (metabotropic) receptors. The AMPA glutamate receptors mediate fast synaptic transmission in the CNS.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

Gene ID: 2890

NCBI Accession: NP_000818

UniProt: P42261

Pathways: PI3K-Akt Signaling