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Tyrosine Hydroxylase antibody (pSer40)
TH
Reactivity: Human, Rat, Mouse
IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Tyrosine Hydroxylase Antibody
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Target
See all Tyrosine Hydroxylase (TH) Antibodies
Tyrosine Hydroxylase (TH)
Binding Specificity
All epitopes for Tyrosine Hydroxylase antibodies
pSer40
Reactivity
All reactivities for Tyrosine Hydroxylase antibodies
Human, Rat, Mouse
Host
All hosts for Tyrosine Hydroxylase antibodies
Rabbit
Clonality
All clonalities for Tyrosine Hydroxylase antibodies
Polyclonal
Conjugate
All conjugates for Tyrosine Hydroxylase antibodies
This Tyrosine Hydroxylase antibody is un-conjugated
Application
All applications for Tyrosine Hydroxylase antibodies
Immunofluorescence (IF)
Specificity
Tyrosine Hydroxylase (Phospho-Ser40) Antibody detects endogenous levels of Tyrosine Hydroxylase only when phosphorylated at serine 40.
Purification
Affinity chromatography
Immunogen
Synthesized phosphopeptide derived from human Tyrosine Hydroxylase around the phosphorylation site of serine 40(R-Q-SP-L-I)
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Alternatives
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Application Details
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Application Notes
Immunofluorescence: 1/100 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Target Details for Tyrosine Hydroxylase
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Target
Tyrosine Hydroxylase (TH)
Alternative Name
Tyrosine 3-Monooxygenase (TH) (TH Products )
Synonyms
DYT14 antibody, DYT5b antibody, TYH antibody, The antibody, CG10118 antibody, DH65B antibody, DTH antibody, Dmel\\CG10118 antibody, Pale antibody, Ple antibody, TH antibody, Th antibody, VII antibody, dTH1 antibody, dTH65B antibody, pale/ple antibody, th antibody, dyt14 antibody, dyt5b antibody, tyh antibody, tyrosine hydroxylase antibody, pale antibody, tyrosine 3-monooxygenase antibody, tyrosine hydroxylase S homeolog antibody, TH antibody, Th antibody, ple antibody, th antibody, th.S antibody, LOC100008895 antibody
Background
Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. Tyrosine hydroxylase is regularly used as a marker for dopaminergic neurons, which is particularly relevant for research into Parkinson's diseaseSynonyms: TYH, Tyrosine 3-hydroxylase
Gene ID
7054
NCBI Accession
NP_000351
UniProt
P07101
Pathways
Dopaminergic Neurogenesis , Response to Water Deprivation , Sensory Perception of Sound , Carbohydrate Homeostasis , Feeding Behaviour
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