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RAB11FIP3 antibody (C-Term)

RAB11FIP3 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN401388
  • Target See all RAB11FIP3 Antibodies
    RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))
    Binding Specificity
    • 4
    • 1
    • 1
    C-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 13
    • 1
    Rabbit
    Clonality
    • 13
    • 1
    Polyclonal
    Conjugate
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAB11FIP3 antibody is un-conjugated
    Application
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is directed against FIP3 protein.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Recombinant protein corresponding to amino acids spanning the carboxyl terminal one- third of human FIP3
    Isotype
    IgG
    Top Product
    Discover our top product RAB11FIP3 Primary Antibody
  • Application Notes
    ELISA: 1/1,000 - 1/3,000. Western Blot: 1/200 - 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.19 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
  • Target
    RAB11FIP3 (RAB11 Family Interacting Protein 3 (Class II) (RAB11FIP3))
    Alternative Name
    RAB11FIP3 (RAB11FIP3 Products)
    Synonyms
    LRRGT00043 antibody, RGD1308952 antibody, MNDPK antibody, RAB11FIP3 antibody, CART1 antibody, Rab11-FIP3 antibody, Cart1 antibody, D030060O14Rik antibody, mKIAA0665 antibody, si:ch211-153c20.4 antibody, zC153C20.4 antibody, RAB11 family interacting protein 3 antibody, NME/NM23 nucleoside diphosphate kinase 4 antibody, RAB11 family interacting protein 3 (class II) antibody, Rab11fip3 antibody, NME4 antibody, RAB11FIP3 antibody, rab11fip3 antibody
    Background
    Rab11 Family-Interacting Protein 3 (FIP3)/Arfophilin-1 and FIP4/Arfophilin-2 are dual effectors for Rab11 and the ADP-ribosylation factor Arf6. Rab11 and Arf6 are involved in membrane delivery from recycling endosomes to the plasma membrane during cytokinesis. The dual Rab11/Arf6 binding proteins, FIP3 and FIP4, function in the delivery of recycling endosomes to the cleavage furrow and are, together with Rab11, essential for completion of abscission, the terminal step of cytokinesis. An interaction between Rab11-FIP3 and ASAP1 has also been identified (personal communication, P. Randazzo, CCR-NCI, Bethesda, MD). ASAP1 is an Arf GTPase-activating protein that has been implicated in the invasive properties of uveal melanoma and mammary carcinoma.Synonyms: ARFO1, Arfophilin-1, Eferin, FIP3-Rab11, KIAA0665, MU-MB-17.148, Rab11 family-interacting protein 3, Rab11-FIP3
    Gene ID
    9727
    NCBI Accession
    NP_001135744
    UniProt
    O75154
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