IL17F antibody

Catalog No. ABIN401099

Product Details anti-IL17F Antibody

Target: IL17F (Interleukin 17F (IL17F))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17F antibody is un-conjugated

Application: Western Blotting (WB), Neutralization (Neut), Enzyme Immunoassay (EIA)

Specificity: In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL17-F in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.

Purification: Purified

Immunogen: Full length recombinant Human IL17-F protein

Isotype: IgG

Application Details

Application Notes: Suitable for use in ELISA and Western blotting. Reactivity is also expected inNeutralizations, Radioimmunoassay and Immunohistochemistry. By western blot a band approximately 15.0 kDa in size corresponding to Human IL17-Fprotein is expected in the appropriate cell lysate or extract. Recommended Dilutions: ELISA: 1/1,000-1/5,000. Western Blot: 1/500-1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.1 mL of deionized water (or equivalent).

Concentration: 1.0 mg/mL.

Buffer: 0.02 M Potassium Phosphate, 0.12 M Sodium Chloride, pH 7.2 without preservatives.

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for IL17F

Target: IL17F (Interleukin 17F (IL17F))

Alternative Name: Interleukin-17F / IL17F (IL17F Products)

Background: IL17-F (also known as ML1, ML-1, IL17F, and IL24) is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/ GFB, and monocyte chemoattractant protein-1.Synonyms: Cytokine ML-1, IL-17F, IL-24, IL24, Interleukin-24

Gene ID: 112744

NCBI Accession: NP_443104

UniProt: Q6NSI0

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity