Choline Kinase alpha antibody (C-Term)

Catalog No. ABIN392815

Product Details anti-Choline Kinase alpha Antibody

Target: Choline Kinase alpha (CHKA)

Binding Specificity: AA 427-457, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Choline Kinase alpha antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This Choline kinase alpha (CHK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 427-457 amino acids from the C-terminal region of human Choline kinase alpha (CHK).

Clone: RB5497

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-Choline Kinase alpha antibody (ABIN392815)

Zhang, Chen, Yang, Li, Bao, Wu, Jiang: "CHKA mediates the poor prognosis of lung adenocarcinoma and acts as a prognostic indicator." in: Oncology letters, Vol. 12, Issue 3, pp. 1849-1853, (2016) (PubMed).

Target Details for Choline Kinase alpha

Target: Choline Kinase alpha (CHKA)

Alternative Name: Choline kinase alpha (CHK) (CHKA Products)

Background: The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase alpha is the initial enzyme in the sequence and may play a regulatory role. This protein also catalyzes the phosphorylation of ethanolamine. The antibody for this protein recognizes both isoforms.

Molecular Weight: 52249

Gene ID: 1119

NCBI Accession: NP_001268, NP_997634

UniProt: P35790