NME4 antibody (C-Term)

Catalog No. ABIN392785

Product Details anti-NME4 Antibody

Target: NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))

Binding Specificity: AA 158-187, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NME4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NME4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the C-terminal region of human NME4.

Clone: RB4058

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for NME4

Target: NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))

Alternative Name: NME4 (NME4 Products)

Synonyms: NDPK-D antibody, NM23H4 antibody, nm23-H4 antibody, 2610027N22Rik antibody, 2810024O08Rik antibody, 5730493H09Rik antibody, NM23-M4 antibody, Nm23M4 antibody, NME/NM23 nucleoside diphosphate kinase 4 antibody, NME4 antibody, Nme4 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Molecular Weight: 20659

Gene ID: 4833

NCBI Accession: NP_005000

UniProt: O00746

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process