DGKA antibody (C-Term)

Catalog No. ABIN392729

Product Details anti-DGKA Antibody

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Binding Specificity: AA 598-628, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGKA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DGKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 598-628 amino acids from the C-terminal region of human DGKA.

Clone: RB3872

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DGKA

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Alternative Name: DGKA (DGKA Products)

Synonyms: DAGK antibody, DAGK1 antibody, DGK-alpha antibody, 80kDa antibody, AW146112 antibody, Dagk1 antibody, dgka antibody, zgc:136759 antibody, dagk antibody, dagk1 antibody, dgk-alpha antibody, diacylglycerol kinase alpha antibody, diacylglycerol kinase, alpha antibody, diacylglycerol kinase, alpha 80kDa antibody, diacylglycerol kinase, alpha a antibody, diacylglycerol kinase alpha S homeolog antibody, DGKA antibody, Dgka antibody, dgkaa antibody, Tsp_02164 antibody, dgka antibody, dgka.S antibody

Background: Upon cell stimulation, the kinase DGKA converts the second messenger diacylglycerol into phophatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. DGKA is stimulated by calcium and phosphatidylserine, and is phosphorylated by protein kinase C. Tissue expression is in lymphocytes and oligodengroglial cells. DGKA contains 2 zinc-dependent phorbol-ester and DAG binding domains, and 2 EF-hand calcium binding domains.

Molecular Weight: 82630

Gene ID: 1606

NCBI Accession: NP_001336, NP_958852, NP_958853, NP_963848

UniProt: P23743