Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ZAK antibody (AA 271-300)

ZAK Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB03313-03314 unconjugated
Catalog No. ABIN392643
  • Target See all ZAK Antibodies
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    Binding Specificity
    • 15
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-300
    Reactivity
    • 42
    • 33
    • 17
    • 2
    Human
    Host
    • 52
    • 6
    Rabbit
    Clonality
    • 52
    • 6
    Polyclonal
    Conjugate
    • 32
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZAK antibody is un-conjugated
    Application
    • 32
    • 25
    • 14
    • 13
    • 13
    • 11
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This MLKLAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human MLKLAK.
    Clone
    RB03313-03314
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ZAK Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Pescatore, Esposito, Draber, Walczak, Ursini: "NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II." in: Cell death & disease, Vol. 7, Issue 8, pp. e2346, (2017) (PubMed).

  • Target
    ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
    Alternative Name
    MLKLAK (ZAK Products)
    Background
    MLKLAK is a member of the MAPKKK family of signal transduction molecules. It possesses an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity.
    Molecular Weight
    91155
    Gene ID
    51776
    NCBI Accession
    NP_057737, NP_598407
    UniProt
    Q9NYL2
You are here:
Support