BRD3 antibody (C-Term)

Catalog No. ABIN392610

Product Details anti-BRD3 Antibody

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Binding Specificity: AA 672-702, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This BRD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 672-702 amino acids from the C-terminal region of human BRD3.

Clone: RB3471

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-BRD3 antibody (ABIN392610)

Klein, Kabala, Grabiec, Gay, Kolling, Lin, Gay, Tak, Prinjha, Ospelt, Reedquist: "The bromodomain protein inhibitor I-BET151 suppresses expression of inflammatory genes and matrix degrading enzymes in rheumatoid arthritis synovial fibroblasts." in: Annals of the rheumatic diseases, (2014) (PubMed).

Target Details for BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Alternative Name: BRD3 (BRD3 Products)

Synonyms: ORFX antibody, RING3L antibody, 2410084F24Rik antibody, AW060456 antibody, Fsrg2 antibody, RINGL3 antibody, brd3 antibody, fi36b10 antibody, wu:fa13h06 antibody, wu:fc01d09 antibody, wu:fc74a08 antibody, wu:fi04h10 antibody, wu:fi36b10 antibody, BRD3 antibody, ring3l antibody, fa28f05 antibody, wu:fa28f05 antibody, wu:fc56a11 antibody, wu:fj66d12 antibody, zgc:77289 antibody, bromodomain containing 3 antibody, bromodomain containing 3a antibody, bromodomain containing 3 S homeolog antibody, bromodomain-containing protein 3 antibody, bromodomain containing 3b antibody, BRD3 antibody, Brd3 antibody, brd3a antibody, brd3.S antibody, LOC100410652 antibody, LOC100354641 antibody, brd3b antibody

Background: This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

Molecular Weight: 79542

Gene ID: 8019

NCBI Accession: NP_031397

UniProt: Q15059

Pathways: Chromatin Binding