GARS antibody (C-Term)

Catalog No. ABIN392465

Product Details anti-GARS Antibody

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Binding Specificity: AA 706-739, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GARS antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-739 amino acids from the C-terminal region of human GARS.

Clone: RB11217

Isotype: IgG

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GARS

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Alternative Name: GARS (GARS Products)

Synonyms: CMT2D antibody, DSMAV antibody, GlyRS antibody, HMN5 antibody, SMAD1 antibody, Aat-gly antibody, CG6778 antibody, Dmel\\CG6778 antibody, GRS antibody, gars antibody, team antibody, RGD1559871 antibody, GENA202 antibody, Gena201 antibody, Nmf249 antibody, Sgrp23 antibody, GB13467 antibody, MGC79495 antibody, fb02f03 antibody, si:dkey-276i5.1 antibody, wu:fb02f03 antibody, NI36_08435 antibody, glycyl-tRNA synthetase antibody, Glycyl-tRNA synthetase antibody, glycine--tRNA ligase antibody, glycyl-tRNA synthetase L homeolog antibody, Glycine--tRNA ligase antibody, GARS antibody, GlyRS antibody, Gars antibody, LOC408392 antibody, gars.L antibody, gars antibody, LOC692991 antibody, glyQ antibody, TTHA0543 antibody, NI36_RS08405 antibody

Background: GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.

Molecular Weight: 83166

Gene ID: 2617

NCBI Accession: NP_002038

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process