IARS2 antibody (AA 600-628)

Catalog No. ABIN2841959

Product Details anti-IARS2 Antibody

Target: IARS2 (Isoleucyl-tRNA Synthetase 2, Mitochondrial (IARS2))

Binding Specificity: AA 600-628

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pr

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This IARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 600-628 amino acids from the Central region of human IARS2.

Clone: RB14820

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for IARS2

Target: IARS2 (Isoleucyl-tRNA Synthetase 2, Mitochondrial (IARS2))

Alternative Name: IARS2 (IARS2 Products)

Synonyms: RGD1311857 antibody, si:zc214p16.3 antibody, si:ch211-214p16.3 antibody, 2010002H18Rik antibody, C79125 antibody, ILERS antibody, ileRS antibody, isoleucyl-tRNA synthetase 2, mitochondrial antibody, isoleucine-tRNA synthetase 2, mitochondrial antibody, Iars2 antibody, IARS2 antibody, iars2 antibody

Background: IARS2 belongs to the class-I aminoacyl-tRNA synthetase family. Members of class I have two highly conserved sequence motifs. They aminoacylate at the 2'-OH of an adenosine nucleotide, and are usually monomeric or dimeric (one or two subunits, respectively). Both classes of aminoacyl-tRNA synthetases are multidomain proteins. The catalytic domains of all the aaRSs of a given class are found to be homologous to one another, while class I and class II aaRSs are unrelated to one another. The class I aaRSs have the ubiquitous Rossmann fold and have the antiparallel beta-strands architecture while the class II aaRSs have a unique fold made up of antiparallel beta-strands.

Molecular Weight: 113792

Gene ID: 55699

NCBI Accession: NP_060530

UniProt: Q9NSE4