Filamin A antibody (AA 1025-1054)

Catalog No. ABIN392193

Product Details anti-Filamin A Antibody

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Binding Specificity: AA 1025-1054

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Filamin A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FLNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from human FLNA.

Clone: RB14246

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Filamin A

Target: Filamin A (FLNA) (Filamin A, alpha (FLNA))

Alternative Name: FLNA (FLNA Products)

Synonyms: ABP-280 antibody, ABPX antibody, CSBS antibody, CVD1 antibody, FLN antibody, FLN-A antibody, FLN1 antibody, FMD antibody, MNS antibody, NHBP antibody, OPD antibody, OPD1 antibody, OPD2 antibody, XLVD antibody, XMVD antibody, fb98b06 antibody, wu:fb98b06 antibody, wu:fd09g03 antibody, wu:fd49a06 antibody, Dilp2 antibody, F730004A14Rik antibody, Fln1 antibody, filamin-1 antibody, RGD1560614 antibody, MGC147094 antibody, CG3937 antibody, Cher antibody, Dmel\\CG3937 antibody, Fil antibody, joy antibody, sko antibody, filamin A antibody, filamin A, alpha (actin binding protein 280) antibody, filamin, alpha antibody, filamin-A antibody, cheerio antibody, FLNA antibody, flna antibody, Flna antibody, LOC587317 antibody, cher antibody, LOC100380643 antibody

Background: Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.

Molecular Weight: 280739

Gene ID: 2316

NCBI Accession: NP_001104026, NP_001447

UniProt: P21333

Pathways: TCR Signaling, Maintenance of Protein Location