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Filamin A antibody (AA 1025-1054)
FLNA
Reactivity: Human
WB, IHC (p), IF, FACS
Host: Rabbit
Polyclonal
RB14246
unconjugated
Product Details anti-Filamin A Antibody
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Target
See all Filamin A (FLNA) Antibodies
Filamin A (FLNA)
(Filamin A, alpha (FLNA))
Binding Specificity
All epitopes for Filamin A antibodies
AA 1025-1054
Reactivity
All reactivities for Filamin A antibodies
Human
Host
All hosts for Filamin A antibodies
Rabbit
Clonality
All clonalities for Filamin A antibodies
Polyclonal
Conjugate
All conjugates for Filamin A antibodies
This Filamin A antibody is un-conjugated
Application
All applications for Filamin A antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)
Predicted Reactivity
M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FLNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from human FLNA.
Clone
RB14246
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for Filamin A
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Target
Filamin A (FLNA)
(Filamin A, alpha (FLNA))
Alternative Name
FLNA (FLNA Products )
Background
Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
Molecular Weight
280739
Gene ID
2316
NCBI Accession
NP_001104026 , NP_001447
UniProt
P21333
Pathways
TCR Signaling , Maintenance of Protein Location
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