Neurotrophin 3 antibody (AA 122-151)

Catalog No. ABIN392182

Product Details anti-Neurotrophin 3 Antibody

Target: Neurotrophin 3 (NTF3)

Binding Specificity: AA 122-151

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurotrophin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, C, M, Pig, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This NTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 122-151 amino acids from the Central region of human NTF3.

Clone: RB14463

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Neurotrophin 3

Target: Neurotrophin 3 (NTF3)

Alternative Name: NTF3 (NTF3 Products)

Synonyms: HDNF antibody, NGF-2 antibody, NGF2 antibody, NT3 antibody, NT-3 antibody, wu:fl98d04 antibody, hdnf antibody, ngf-2 antibody, ngf2 antibody, nt-3 antibody, nt3 antibody, NTF3 antibody, AI316846 antibody, AI835689 antibody, Nt3 antibody, Ntf-3 antibody, neurotrophin 3 antibody, neurotrophin 3 S homeolog antibody, neurotrophin 3 L homeolog antibody, NTF3 antibody, ntf3 antibody, ntf3.S antibody, Ntf3 antibody, ntf3.L antibody

Background: NTF3 is a member of the neurotrophin family that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.

Molecular Weight: 29355

Gene ID: 4908

NCBI Accession: NP_001096124, NP_002518

UniProt: P20783

Pathways: RTK Signaling, Neurotrophin Signaling Pathway