GHRH antibody (N-Term)

Catalog No. ABIN392174

Product Details anti-GHRH Antibody

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Binding Specificity: AA 8-34, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHRH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GHRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-34 amino acids from the N-terminal region of human GHRH.

Clone: RB14533

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GHRH

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Alternative Name: GHRH (GHRH Products)

Synonyms: GHRF antibody, GRF antibody, INN antibody, PACAP antibody, grf antibody, Ghrf antibody, growth hormone releasing hormone antibody, adenylate cyclase activating polypeptide 1 antibody, GHRH antibody, ADCYAP1 antibody, ghrh antibody, Ghrh antibody, LOC780526 antibody

Background: GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this protein are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Molecular Weight: 12447

Gene ID: 2691

NCBI Accession: NP_001171660, NP_066567

UniProt: P01286

Pathways: Hormone Transport, Hormone Activity, cAMP Metabolic Process