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SMAD4 antibody (AA 255-284)
SMAD4
Reactivity: Human, Mouse
WB, IF
Host: Rabbit
Polyclonal
RB14714
unconjugated
Product Details anti-SMAD4 Antibody
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Target
See all SMAD4 Antibodies
SMAD4
(SMAD Family Member 4 (SMAD4))
Binding Specificity
All epitopes for SMAD4 antibodies
AA 255-284
Reactivity
All reactivities for SMAD4 antibodies
Human, Mouse
Host
All hosts for SMAD4 antibodies
Rabbit
Clonality
All clonalities for SMAD4 antibodies
Polyclonal
Conjugate
All conjugates for SMAD4 antibodies
This SMAD4 antibody is un-conjugated
Application
All applications for SMAD4 antibodies
Western Blotting (WB), Immunofluorescence (IF)
Predicted Reactivity
Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SMAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from human SMAD4.
Clone
RB14714
Isotype
Ig Fraction
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Discover our top product SMAD4 Primary Antibody
Alternatives
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Application Details
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Application Notes
IF: 1:10~50. WB: 1:1000. WB: 1:2000. WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
References for anti-SMAD4 antibody (ABIN392165)
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Lessard, Rivas, Alves-Wagner, Hirshman, Gallagher, Constantin-Teodosiu, Atkins, Greenhaff, Qi, Gustafsson, Fielding, Timmons, Britton, Koch, Goodyear : "Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. " in: Diabetes , Vol. 62 , Issue 8 , pp. 2717-27 , (2013 ) (PubMed ).
Target Details for SMAD4
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Target
SMAD4
(SMAD Family Member 4 (SMAD4))
Alternative Name
SMAD4 (SMAD4 Products )
Synonyms
smad4 antibody, DPC4 antibody, JIP antibody, MADH4 antibody, MYHRS antibody, AW743858 antibody, D18Wsu70e antibody, Madh4 antibody, XSmad4alpha antibody, Xsmad4 antibody, dpc4 antibody, jip antibody, madh4 antibody, xsmad4a antibody, SMAD family member 4 antibody, Smad4 protein antibody, SMAD family member 4, gene 1 L homeolog antibody, SMAD4 antibody, smad4 antibody, Smad4 antibody, smad4.1.L antibody
Background
SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Molecular Weight
60439
Gene ID
4089
NCBI Accession
NP_005350
UniProt
Q13485
Pathways
Cell Division Cycle , Chromatin Binding , Autophagy
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