Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-205 amino acids from the Central region of human TEC.
CHN antibody, CSMF antibody, MINOR antibody, NOR1 antibody, TEC antibody, AI573420 antibody, NOR-1 antibody, Nor1 antibody, NOR-2 antibody, NR4A3 antibody, Nr4a3 antibody, nuclear receptor subfamily 4 group A member 3 antibody, nuclear receptor subfamily 4, group A, member 3 antibody, NR4A3 antibody, Nr4a3 antibody, nr4a3 antibody
Background
TEC belongs to the TEC subfamily of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. TEC family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. TEC kinase is an integral component of T cell signaling and has a distinct role in T cell activation. TEC may be associated with myelodysplastic syndrome.