PDGFRL antibody (C-Term)

Catalog No. ABIN392037

Product Details anti-PDGFRL Antibody

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Binding Specificity: AA 328-357, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-357 amino acids from the C-terminal region of human PDGFRL.

Clone: RB2001

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PDGFRL (PDGFRL Products)

Synonyms: zgc:56104 antibody, zgc:77677 antibody, MGC82397 antibody, PDGFRL antibody, pdgrl antibody, prlts antibody, MGC107901 antibody, PDGRL antibody, PRLTS antibody, 1110039P19Rik antibody, AV013190 antibody, platelet-derived growth factor receptor-like antibody, platelet derived growth factor receptor like L homeolog antibody, platelet derived growth factor receptor like antibody, pdgfrl antibody, pdgfrl.L antibody, PDGFRL antibody, Pdgfrl antibody

Background: PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.

Molecular Weight: 41861

Gene ID: 5157

NCBI Accession: NP_006198

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling